A GLP-1/GIP/GCG receptor agonist for weight loss and metabolic health.
Retatrutide is a cutting-edge investigational drug designed to address obesity and type 2 diabetes through a triple hormone approach.
GLP-1 (Glucagon-Like Peptide-1)** – reduces appetite and improves insulin response
GIP (Glucose-Dependent Insulinotropic Polypeptide)** – supports insulin secretion and metabolic balance
Glucagon receptor – boosts energy expenditure and fat burning
Explore the most important features we have
Appetite Suppression
Increases Energy Use
Reduces Inflammation
This combination helps regulate hunger, stabilize blood sugar, and accelerate weight loss. By mimicking the body’s natural hormonal signals, Retatrutide provides a more comprehensive metabolic effect compared to traditional GLP-1-only drugs.
Alexandre Pop, Head of Marketing
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Over 24% weight reduction in clinical trial participants
Participants in phase 2 trials lost more than 24% of their body weight over 48 weeks — a record-high response in obesity treatment trials.
Significant reduction in HbA1c in T2D patients
Retatrutide showed strong glucose-lowering effects, with major reductions in HbA1c in patients with type 2 diabetes, alongside weight loss.
Safe and well-tolerated in trials
Most side effects were mild to moderate (like nausea), and similar to those seen with other incretin-based therapies.
Triple hormone mechanism improves metabolic regulation
Activating GLP-1, GIP, and glucagon receptors leads to appetite suppression, enhanced insulin sensitivity, and increased fat metabolism.
Retatrutide is a novel multi-receptor agonist that targets the GLP-1, GIP, and glucagon receptors to deliver powerful benefits in weight reduction, blood sugar control, and overall metabolic regulation. By combining these three hormonal pathways, Retatrutide offers a more comprehensive approach than existing single-pathway therapies.
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